In the last decade (especially from 2013–2014) there has been an increase in the use of NPS in Georgia. There is a lack of data on non-injection drug use in the country. Prevalence of NPS use is unknown and virtually impossible to determine. The main reasons for choosing NPS are: cheapness, more availability and more potency. The study was conducted according to the methodology developed by EHRA and the Principal Investigator from the School of Law, Swansea University. The main difficulties were related to the availability of consolidated information, since the national monitoring center is newly created in the country and information on NPS use is scattered and not integrated. Furthermore, the existing information is not enough to draw significant conclusions about NPS use trends and patterns in the country.